This week's installation of the best memes on the Web features some familiar faces with some new twists. The "annoying childhood friend" and the "girl with first world problems" found their way into the group again, and even the Pope could not escape meme-madness. Of course, we have the return of Zeddie Little, aka The Ridiculously Photogenic Guy

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Annoying Facebook Girl
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Annoying Childhood Friend meme
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Nine lives meme
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Bad Luck Brian
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Pope meme
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Keanu Reeves meme
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Socially Awkward Penguin
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