Lainie Kazan — ‘Harry and the Hendersons’ Then and Now

Then: Kazen made an impression as nosy neighbor Irene Moffat. The same year the film was released, she starred alongside Patty Duke and a young Teri Hatcher in the short-lived sitcom 'Karen’s Song.'

Now: Still a working actress, Kazan played Maxine Rosen on the seventh season of 'Desperate Housewives.' You may also remember her as Gail, the mother of Nick Swardson's character, in 'You Don't Mess With the Zohan.'