Then: Though he lost the 'Wanna Be a VJ' contest to the spacey Jesse Camp, Holmes impressed MTV execs with his poise and expansive music knowledge. So, he was hired to do celebrity interviews. From there, Holmes went on to host a bunch of MTV programs, including '120 Minutes,' 'Total Request Live,' and 'Say What? Karaoke.'

Now: Holmes has continued to work in television as an actor and television personality, appearing on FX's 'DVD on TV,' the sitcom 'Ben and Kate' and the wacky cop comedy series 'Reno 911!' In 2002, he came out publicly in 'Out' magazine. He has since been instrumental in the ''It Gets Better'' project. Currently, he hosts the daily video podcast 'A Drink With Dave.' Keep up with Holmes on Twitter.